Session 3 - Case reports – risk factors for anti-CGRP targeting treatments

Marja-Liisa Sumelahti

MD, PhD, Specialist in Neurology, Faculty of Medicine and Health Technology, Tampere University, Finland

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an hereditary angiopathy caused by mutations in the NOTCH3 gene. It is rare, with a prevalence of 5 per 100,000; it is associated with an increased risk of transient ischaemic attack, cognitive defects and migraine developing after age 45, and has a highly variable progressive clinical course.